Recent studies on A-GPC have shown a potential benefit to athletic performance. A Japanese study investigated the effects of a single dose of A-GCP on hormone release in healthy young males. Surprisingly a single dose of Alpha-GCP resulted in a substantial change in growth hormone release within one hour.
At 60 minutes, growth hormone levels acute increased by 290% from the baseline hormone level and returned to baseline by the second hour. Also observed, was the growth hormone’s actions of increasing fatty acid oxidation, as indicated by rises in free fatty acids and ketone bodies. The authors proposed that the increase in circulating choline may briefly block the negative feedback mechanism governing Growth Hormone release.
Short supplementation periods of 6 days have been shown to improve strength in college-aged athletes directly. A study conducted at the University of Louisianna used a crossover design that measured the force generated in deadlift and bench press style movements.
The study found a significant increase of 3% improvement in lower body strength with Alpha-GPC supplementation. The study cited the previous research of cholinergic transmission at neural-muscular as a potential mechanism, however, did not have direct evidence for the mechanism leading to improved strength.
The cumulative evidence from animal model and human studies support the role of Alpha-GPC as a well tolerated cognitive enhancing compound with ergogenic properties. The soy lecithin isolate contains a phospholipid that permits incorporation into neuronal cell membranes and utilisation as a cholinergic neurotransmitter precursor.
Associated with the increase in circulating choline levels was a transient elevation in growth hormone. Even a short period of supplementation with aGPC proved to be beneficial to muscle strength
Recommended Usage & Natural Sources Of Alpha GPC
Alpha GPC is approximately 40% choline by weight, and as such 1,000 mg Alpha-GPC confers about 400 mg of dietary choline. A standard dosage of Alpha-GPC is 300-600 mg, according to the most common label doses.
This dose is following the study using Alpha-GPC to enhance power output and the two studies noting an increase in growth hormone secretion and is likely a good dose to take for athletes.
Game ONN contains a dosage of 300mg per 3 Capsule serving.